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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscLPutative hydrolase (HAD superfamily) (fragment); Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (158 aa)    
Predicted Functional Partners:
dtd
D-tyrosyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
      0.750
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.691
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.617
Ldb0226
Cation:Proton Antiporter.
     
 0.571
hsdM
Type I restriction-modification system, modification subunit.
      
 0.552
hsdR
Conserved hypothetical protein (fragment); Subunit R is required for both nuclease and ATPase activities, but not for modification.
      
 0.551
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.515
prsA,
Putative peptidylprolyl isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
     
 0.512
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.484
Ldb1707
Acetaldehyde dehydrogenase.
  
  
 0.484
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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