node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ldb0540 | Ldb0541 | Ldb0540 | Ldb0541 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | ATP-dependent helicase (DEAD/DEAH box family). | 0.813 |
Ldb0540 | Ldb0542 | Ldb0540 | Ldb0542 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | PTS system, enzyme IIC component (putative cellobiose-specific); The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | 0.776 |
Ldb0541 | Ldb0540 | Ldb0541 | Ldb0540 | ATP-dependent helicase (DEAD/DEAH box family). | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | 0.813 |
Ldb0541 | Ldb0542 | Ldb0541 | Ldb0542 | ATP-dependent helicase (DEAD/DEAH box family). | PTS system, enzyme IIC component (putative cellobiose-specific); The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | 0.784 |
Ldb0541 | dnaJ | Ldb0541 | Ldb1312 | ATP-dependent helicase (DEAD/DEAH box family). | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | 0.705 |
Ldb0541 | fusA | Ldb0541 | Ldb0394 | ATP-dependent helicase (DEAD/DEAH box family). | Translation elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G [...] | 0.705 |
Ldb0541 | ppiB | Ldb0541 | Ldb1104 | ATP-dependent helicase (DEAD/DEAH box family). | Aromatic amino acid aminotransferase (fragment); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.677 |
Ldb0541 | rny | Ldb0541 | Ldb0600 | ATP-dependent helicase (DEAD/DEAH box family). | Putative phosphohydrolase (HD superfamily); Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. | 0.654 |
Ldb0541 | rplC | Ldb0541 | Ldb0396 | ATP-dependent helicase (DEAD/DEAH box family). | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.710 |
Ldb0541 | rplD | Ldb0541 | Ldb0397 | ATP-dependent helicase (DEAD/DEAH box family). | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.706 |
Ldb0541 | rplJ | Ldb0541 | Ldb1658 | ATP-dependent helicase (DEAD/DEAH box family). | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.659 |
Ldb0541 | rplM | Ldb0541 | Ldb0428 | ATP-dependent helicase (DEAD/DEAH box family). | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.668 |
Ldb0542 | Ldb0540 | Ldb0542 | Ldb0540 | PTS system, enzyme IIC component (putative cellobiose-specific); The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | 0.776 |
Ldb0542 | Ldb0541 | Ldb0542 | Ldb0541 | PTS system, enzyme IIC component (putative cellobiose-specific); The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | ATP-dependent helicase (DEAD/DEAH box family). | 0.784 |
dnaJ | Ldb0541 | Ldb1312 | Ldb0541 | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | ATP-dependent helicase (DEAD/DEAH box family). | 0.705 |
dnaJ | fusA | Ldb1312 | Ldb0394 | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | Translation elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G [...] | 0.867 |
dnaJ | ppiB | Ldb1312 | Ldb1104 | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | Aromatic amino acid aminotransferase (fragment); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.856 |
dnaJ | rplC | Ldb1312 | Ldb0396 | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.746 |
dnaJ | rplD | Ldb1312 | Ldb0397 | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.593 |
dnaJ | rplM | Ldb1312 | Ldb0428 | Chaperone protein DnaJ (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interac [...] | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.751 |