ppnK protein (Lactobacillus delbrueckii) - STRING interaction network

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ppnK

NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa)

Predicted Functional Partners:

nadE

0.947

nadD

0.942

Ldb0172

0.917

Ldb0485

0.900

Ldb0584

0.875

Ldb0586

0.851

Ldb0583

0.652

coiA

0.606

Ldb1421

0.576

pta

0.571

Your Current Organism:

Lactobacillus delbrueckii

NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ldb0172	Ldb0485	Ldb0172	Ldb0485	NAD-dependent protein deacetylase (Sir2 family).	Putative hydrolase (NUDIX family).	0.911
Ldb0172	nadD	Ldb0172	Ldb1498	NAD-dependent protein deacetylase (Sir2 family).	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.924
Ldb0172	nadE	Ldb0172	Ldb0455	NAD-dependent protein deacetylase (Sir2 family).	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.918
Ldb0172	ppnK	Ldb0172	Ldb0585	NAD-dependent protein deacetylase (Sir2 family).	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.917
Ldb0485	Ldb0172	Ldb0485	Ldb0172	Putative hydrolase (NUDIX family).	NAD-dependent protein deacetylase (Sir2 family).	0.911
Ldb0485	nadD	Ldb0485	Ldb1498	Putative hydrolase (NUDIX family).	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.905
Ldb0485	nadE	Ldb0485	Ldb0455	Putative hydrolase (NUDIX family).	NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.905
Ldb0485	ppnK	Ldb0485	Ldb0585	Putative hydrolase (NUDIX family).	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.900
Ldb0583	Ldb0584	Ldb0583	Ldb0584	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	0.602
Ldb0583	Ldb0586	Ldb0583	Ldb0586	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	Pseudouridylate synthase.	0.699
Ldb0583	coiA	Ldb0583	Ldb0582	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	Putative competence protein CoiA (fragment).	0.699
Ldb0583	ppnK	Ldb0583	Ldb0585	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.652
Ldb0584	Ldb0583	Ldb0584	Ldb0583	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	0.602
Ldb0584	Ldb0586	Ldb0584	Ldb0586	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	Pseudouridylate synthase.	0.837
Ldb0584	coiA	Ldb0584	Ldb0582	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	Putative competence protein CoiA (fragment).	0.606
Ldb0584	ppnK	Ldb0584	Ldb0585	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.875
Ldb0586	Ldb0583	Ldb0586	Ldb0583	Pseudouridylate synthase.	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	0.699
Ldb0586	Ldb0584	Ldb0586	Ldb0584	Pseudouridylate synthase.	Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.	0.837
Ldb0586	coiA	Ldb0586	Ldb0582	Pseudouridylate synthase.	Putative competence protein CoiA (fragment).	0.596
Ldb0586	ppnK	Ldb0586	Ldb0585	Pseudouridylate synthase.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.851

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