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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ezrASeptation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (572 aa)    
Predicted Functional Partners:
ftsQ
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
   
 0.931
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
      
 0.881
Ldb1015
Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
 
 0.813
Ldb1526
ABC transporter, permease protein.
  
     0.772
Ldb1598
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
  
     0.770
mecA
Negative regulator of competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family.
  
     0.747
Ldb0733
Conserved hypothetical membrane protein.
 
     0.746
dnaB
Chromosome replication initiation/membrane attachment protein DnaB.
 
     0.746
Ldb0685
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
 
     0.745
Ldb0724
Putative cysteine sulfinate desulfinase/cysteine desulfurase.
       0.740
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.