| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ldb0761 | Ldb1478 | Ldb0761 | Ldb1478 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | 0.700 |
| Ldb0761 | ezrA | Ldb0761 | Ldb0723 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.525 |
| Ldb0761 | rnj | Ldb0761 | Ldb0760 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | Putative hydrolase (metallo-beta-lactamase superfamily); An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.895 |
| Ldb0761 | rpoA | Ldb0761 | Ldb0422 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.570 |
| Ldb0761 | rpoB | Ldb0761 | Ldb0386 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.570 |
| Ldb0761 | rpoC | Ldb0761 | Ldb0387 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.570 |
| Ldb0761 | rpoE | Ldb0761 | Ldb0353 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.750 |
| Ldb0761 | rpoZ | Ldb0761 | Ldb1414 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.643 |
| Ldb0761 | sigA, | Ldb0761 | Ldb1246 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | RNA polymerase sigma factor RpoD (Sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.525 |
| Ldb0761 | spx | Ldb0761 | Ldb0578 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | Conserved hypothetical protein (ArsC family); Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.526 |
| Ldb1478 | Ldb0761 | Ldb1478 | Ldb0761 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | 0.700 |
| ezrA | Ldb0761 | Ldb0723 | Ldb0761 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | 0.525 |
| ezrA | rpoE | Ldb0723 | Ldb0353 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.438 |
| rnj | Ldb0761 | Ldb0760 | Ldb0761 | Putative hydrolase (metallo-beta-lactamase superfamily); An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | 0.895 |
| rpoA | Ldb0761 | Ldb0422 | Ldb0761 | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0356 family. | 0.570 |
| rpoA | rpoB | Ldb0422 | Ldb0386 | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoC | Ldb0422 | Ldb0387 | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoE | Ldb0422 | Ldb0353 | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.564 |
| rpoA | rpoZ | Ldb0422 | Ldb1414 | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.998 |
| rpoA | sigA, | Ldb0422 | Ldb1246 | DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase sigma factor RpoD (Sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.663 |
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