Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Ldb0876Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (204 aa)    
Predicted Functional Partners:
Ldb0878
Two-component system, sensor histidine kinase.
 
     0.938
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.922
Ldb0584
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
  
  
 
0.915
ppx
Exopolyphosphatase.
  
  
 0.912
rtpR
Ribonucleoside-triphosphate reductase; Belongs to the class II ribonucleoside-triphosphate reductase family.
    
  0.900
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
    
  0.900
Ldb0877
Two-component system, response regulator.
     0.890
folKE
2-Amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase / GTP cyclohydrolase I.
     
 0.801
trmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.609
gidA
GidA (Glucose inhibited division protein A); NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
   
    0.547
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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