STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaAHydroxymethylglutaryl-CoA reductase. (394 aa)    
Predicted Functional Partners:
mvaS
Hydroxymethylglutaryl-coenzyme A synthase.
 
 0.999
mvk
Mevalonate kinase.
 0.999
Ldb0879
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.978
mvaD
Mevalonate diphosphate decarboxylase.
 
  
 0.927
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.792
mvaK
Phosphomevalonate kinase.
 
 
 0.755
Ldb0882
Conserved hypothetical membrane protein.
       0.660
crtE
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.560
Ldb0447
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
    
 
 0.479
Ldb0172
NAD-dependent protein deacetylase (Sir2 family).
  
  
 0.465
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.