Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbpPenicillin-binding protein. (704 aa)    
Predicted Functional Partners:
pbp1A
Penicillin-binding protein 1A; Bifunctional protein (transglycosylase/transpeptidase).
 
 0.975
pbp2A
Penicillin-binding protein 2A; Bifunctional protein (transglycosylase/transpeptidase).
 
 0.969
rodA
Rod-shape determining protein; Belongs to the SEDS family.
 
 
 0.966
dacA
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.959
mreC
Cell shape determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.949
ftsI
Cell division protein FtsI; Penicillin-binding protein.
 
  
0.932
ftsW
Cell division protein FtsW; Belongs to the SEDS family.
 
 
 0.910
ftsQ
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
 
 0.901
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
   
 0.794
ddl
D-alanine--D-alanine ligase; Cell wall formation.
  
 
 0.788
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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