| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ldb0231 | dltA | Ldb0231 | Ldb2148 | Putative transcriptional regulator (LytR family). | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.900 |
| Ldb0231 | dltB | Ldb0231 | Ldb2147 | Putative transcriptional regulator (LytR family). | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.901 |
| Ldb0231 | dltC | Ldb0231 | Ldb2146 | Putative transcriptional regulator (LytR family). | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.900 |
| Ldb0231 | dltD | Ldb0231 | Ldb2145 | Putative transcriptional regulator (LytR family). | D-alanyl transfer protein DltD. | 0.900 |
| Ldb1644 | dltA | Ldb1644 | Ldb2148 | Putative penicillin binding protein. | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.670 |
| Ldb1644 | dltB | Ldb1644 | Ldb2147 | Putative penicillin binding protein. | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.774 |
| Ldb1644 | dltC | Ldb1644 | Ldb2146 | Putative penicillin binding protein. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.653 |
| Ldb1644 | dltD | Ldb1644 | Ldb2145 | Putative penicillin binding protein. | D-alanyl transfer protein DltD. | 0.709 |
| Ldb2032 | dltA | Ldb2032 | Ldb2148 | Putative transcriptional regulator (LytR family). | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.900 |
| Ldb2032 | dltB | Ldb2032 | Ldb2147 | Putative transcriptional regulator (LytR family). | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.901 |
| Ldb2032 | dltC | Ldb2032 | Ldb2146 | Putative transcriptional regulator (LytR family). | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.900 |
| Ldb2032 | dltD | Ldb2032 | Ldb2145 | Putative transcriptional regulator (LytR family). | D-alanyl transfer protein DltD. | 0.900 |
| Ldb2149 | dltA | Ldb2149 | Ldb2148 | 6 Protein of unknown function, without similarity to other proteins. | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.741 |
| Ldb2149 | dltB | Ldb2149 | Ldb2147 | 6 Protein of unknown function, without similarity to other proteins. | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.741 |
| Ldb2149 | dltC | Ldb2149 | Ldb2146 | 6 Protein of unknown function, without similarity to other proteins. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.533 |
| Ldb2149 | dltD | Ldb2149 | Ldb2145 | 6 Protein of unknown function, without similarity to other proteins. | D-alanyl transfer protein DltD. | 0.533 |
| dltA | Ldb0231 | Ldb2148 | Ldb0231 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | Putative transcriptional regulator (LytR family). | 0.900 |
| dltA | Ldb1644 | Ldb2148 | Ldb1644 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | Putative penicillin binding protein. | 0.670 |
| dltA | Ldb2032 | Ldb2148 | Ldb2032 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | Putative transcriptional regulator (LytR family). | 0.900 |
| dltA | Ldb2149 | Ldb2148 | Ldb2149 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 6 Protein of unknown function, without similarity to other proteins. | 0.741 |
