| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ldb2149 | Ldb2150 | Ldb2149 | Ldb2150 | 6 Protein of unknown function, without similarity to other proteins. | Conserved hypothetical membrane protein. | 0.447 |
| Ldb2149 | dltA | Ldb2149 | Ldb2148 | 6 Protein of unknown function, without similarity to other proteins. | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.741 |
| Ldb2149 | dltB | Ldb2149 | Ldb2147 | 6 Protein of unknown function, without similarity to other proteins. | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.741 |
| Ldb2149 | dltC | Ldb2149 | Ldb2146 | 6 Protein of unknown function, without similarity to other proteins. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.533 |
| Ldb2149 | dltD | Ldb2149 | Ldb2145 | 6 Protein of unknown function, without similarity to other proteins. | D-alanyl transfer protein DltD. | 0.533 |
| Ldb2150 | Ldb2149 | Ldb2150 | Ldb2149 | Conserved hypothetical membrane protein. | 6 Protein of unknown function, without similarity to other proteins. | 0.447 |
| Ldb2150 | dltA | Ldb2150 | Ldb2148 | Conserved hypothetical membrane protein. | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.435 |
| Ldb2150 | dltB | Ldb2150 | Ldb2147 | Conserved hypothetical membrane protein. | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.435 |
| dltA | Ldb2149 | Ldb2148 | Ldb2149 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 6 Protein of unknown function, without similarity to other proteins. | 0.741 |
| dltA | Ldb2150 | Ldb2148 | Ldb2150 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | Conserved hypothetical membrane protein. | 0.435 |
| dltA | dltB | Ldb2148 | Ldb2147 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.999 |
| dltA | dltC | Ldb2148 | Ldb2146 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.999 |
| dltA | dltD | Ldb2148 | Ldb2145 | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | D-alanyl transfer protein DltD. | 0.997 |
| dltB | Ldb2149 | Ldb2147 | Ldb2149 | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 6 Protein of unknown function, without similarity to other proteins. | 0.741 |
| dltB | Ldb2150 | Ldb2147 | Ldb2150 | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | Conserved hypothetical membrane protein. | 0.435 |
| dltB | dltA | Ldb2147 | Ldb2148 | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.999 |
| dltB | dltC | Ldb2147 | Ldb2146 | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.999 |
| dltB | dltD | Ldb2147 | Ldb2145 | D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | D-alanyl transfer protein DltD. | 0.999 |
| dltC | Ldb2149 | Ldb2146 | Ldb2149 | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 6 Protein of unknown function, without similarity to other proteins. | 0.533 |
| dltC | dltA | Ldb2146 | Ldb2148 | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | D-alanine-activating enzyme (D-alanine-D-alanylcarrier protein ligase); Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the [...] | 0.999 |
STRING v12.5 is now available!
