STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR00526.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (137 aa)    
Predicted Functional Partners:
queE
7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.999
folE
GTP cyclohydrolase I.
  
 
 0.993
queC
preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
  
 0.976
SFR14466.1
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
 
 0.905
SFQ95076.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.880
SFQ95407.1
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.880
SFR01163.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.880
SFR10427.1
3-oxoacyl-[acyl-carrier protein] reductase.
    
 0.880
SFR17750.1
2-hydroxycyclohexanecarboxyl-CoA dehydrogenase.
    
 0.880
SFQ99272.1
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases.
    
  0.876
Your Current Organism:
Desulfallas geothermicus
NCBI taxonomy Id: 39060
Other names: D. geothermicus, DSM 3669, Desulfotomaculum geothermicum, NBRC 112753, strain BSD
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