STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR06591.1Nicotinamidase/pyrazinamidase. (177 aa)    
Predicted Functional Partners:
SFR05392.1
Nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family.
 
 
 0.926
SFR01138.1
5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
    
 0.801
SFR06586.1
Histidinol-phosphatase (PHP family); Belongs to the PHP hydrolase family. HisK subfamily.
  
    0.793
SFR12951.1
NAD-dependent deacetylase.
 
 0.766
SFR05067.1
NAD-dependent deacetylase.
  
 0.736
cinA
Competence/damage-inducible protein cinA; Belongs to the CinA family.
    
 0.702
SFR06280.1
Pimeloyl-ACP methyl ester carboxylesterase.
  
 0.686
nnrE
NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...]
  
    0.686
SFR06580.1
DNA replication protein DnaD.
       0.685
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.678
Your Current Organism:
Desulfallas geothermicus
NCBI taxonomy Id: 39060
Other names: D. geothermicus, DSM 3669, Desulfotomaculum geothermicum, NBRC 112753, strain BSD
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.