STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEF07319.1Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (337 aa)    
Predicted Functional Partners:
SEF07309.1
Homoserine dehydrogenase.
 
 
 0.998
SEF07329.1
O-acetylhomoserine sulfhydrylase.
 
 0.996
SEE32432.1
Aspartate kinase; Belongs to the aspartokinase family.
   
 0.972
SEE80501.1
Aspartate kinase; Belongs to the aspartokinase family.
   
 0.930
SEF13165.1
Threonine dehydratase.
  
 
 0.887
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.880
SEE92896.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.816
SEE92915.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.815
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
 0.813
SEE84148.1
Serine O-acetyltransferase.
 
  
 0.797
Your Current Organism:
Salinimicrobium catena
NCBI taxonomy Id: 390640
Other names: CGMCC 1.6101, DSM 23553, Flavobacteriaceae bacterium HY1, JCM 14015, S. catena, Salegentibacter catena, Salegentibacter catena Ying et al. 2007, Salinimicrobium catena (Ying et al. 2007) Lim et al. 2008 emend. Nedashkovskaya et al. 2010, strain HY1
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