node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tpet_0445 | Tpet_0446 | Tpet_0445 | Tpet_0446 | PFAM: isochorismatase hydrolase. | Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family. | 0.987 |
Tpet_0445 | Tpet_0449 | Tpet_0445 | Tpet_0449 | PFAM: isochorismatase hydrolase. | Putative diguanylate cyclase. | 0.727 |
Tpet_0445 | pdxS | Tpet_0445 | Tpet_0447 | PFAM: isochorismatase hydrolase. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.773 |
Tpet_0445 | pdxT | Tpet_0445 | Tpet_0448 | PFAM: isochorismatase hydrolase. | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.773 |
Tpet_0446 | Tpet_0445 | Tpet_0446 | Tpet_0445 | Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family. | PFAM: isochorismatase hydrolase. | 0.987 |
Tpet_0446 | Tpet_0449 | Tpet_0446 | Tpet_0449 | Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family. | Putative diguanylate cyclase. | 0.743 |
Tpet_0446 | pdxS | Tpet_0446 | Tpet_0447 | Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.788 |
Tpet_0446 | pdxT | Tpet_0446 | Tpet_0448 | Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family. | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.786 |
Tpet_0449 | Tpet_0445 | Tpet_0449 | Tpet_0445 | Putative diguanylate cyclase. | PFAM: isochorismatase hydrolase. | 0.727 |
Tpet_0449 | Tpet_0446 | Tpet_0449 | Tpet_0446 | Putative diguanylate cyclase. | Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family. | 0.743 |
Tpet_0449 | pdxS | Tpet_0449 | Tpet_0447 | Putative diguanylate cyclase. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.811 |
Tpet_0449 | pdxT | Tpet_0449 | Tpet_0448 | Putative diguanylate cyclase. | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.811 |
Tpet_1050 | Tpet_1664 | Tpet_1050 | Tpet_1664 | PFAM: Transketolase domain protein; Transketolase, central region. | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | 0.929 |
Tpet_1050 | deoB | Tpet_1050 | Tpet_0758 | PFAM: Transketolase domain protein; Transketolase, central region. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.912 |
Tpet_1050 | pdxS | Tpet_1050 | Tpet_0447 | PFAM: Transketolase domain protein; Transketolase, central region. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.807 |
Tpet_1050 | pdxT | Tpet_1050 | Tpet_0448 | PFAM: Transketolase domain protein; Transketolase, central region. | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
Tpet_1050 | prs | Tpet_1050 | Tpet_1163 | PFAM: Transketolase domain protein; Transketolase, central region. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.944 |
Tpet_1050 | rbsK | Tpet_1050 | Tpet_1789 | PFAM: Transketolase domain protein; Transketolase, central region. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.917 |
Tpet_1050 | tal | Tpet_1050 | Tpet_0617 | PFAM: Transketolase domain protein; Transketolase, central region. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.990 |
Tpet_1664 | Tpet_1050 | Tpet_1664 | Tpet_1050 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | PFAM: Transketolase domain protein; Transketolase, central region. | 0.929 |