STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggDNA-(apurinic or apyrimidinic site) lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (207 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
       0.811
Tpet_1107
HflK protein; HflC and HflK could encode or regulate a protease.
       0.793
Tpet_1108
HflC protein; HflC and HflK could regulate a protease.
       0.793
Tpet_1103
PFAM: Chromate transporter.
       0.540
Tpet_1104
PFAM: Chromate transporter.
       0.540
Tpet_1705
PFAM: alpha/beta hydrolase fold.
  
     0.529
Tpet_1575
PFAM: GCN5-related N-acetyltransferase.
  
     0.514
valS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.477
Tpet_1000
Hypothetical protein.
  
     0.444
Tpet_0681
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.441
Your Current Organism:
Thermotoga petrophila
NCBI taxonomy Id: 390874
Other names: T. petrophila RKU-1, Thermotoga petrophila RKU-1, Thermotoga petrophila str. RKU-1, Thermotoga petrophila strain RKU-1, Thermotoga sp. RKU-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.