STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)    
Predicted Functional Partners:
Smal_0453
PFAM: Beta-ketoacyl synthase; KEGG: xcb:XC_3652 beta-ketoacyl-[ACP] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.994
fabV
Trans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.
  
 
 0.972
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 
 0.965
Smal_3909
TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rme:Rmet_4391 3-ketoacyl-(acyl-carrier-protein) reductase.
   
 0.951
Smal_0872
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.937
Smal_1727
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xcb:XC_0429 3-oxoacyl-[ACP] reductase.
   
 0.927
Smal_1707
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; KR domain protein; KEGG: xac:XAC0083 short chain dehydrogenase.
   
 0.926
Smal_1809
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mfa:Mfla_1785 3-ketoacyl-(acyl-carrier-protein) reductase.
   
 0.926
Smal_2069
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mmr:Mmar10_0259 short-chain dehydrogenase/reductase SDR.
   
 0.926
Smal_2168
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xac:XAC0083 short chain dehydrogenase.
   
 0.926
Your Current Organism:
Stenotrophomonas maltophilia R5513
NCBI taxonomy Id: 391008
Other names: S. maltophilia R551-3, Stenotrophomonas maltophilia R551-3, Stenotrophomonas maltophilia str. R551-3, Stenotrophomonas maltophilia strain R551-3
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