STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmel_0774PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (515 aa)    
Predicted Functional Partners:
Tmel_0775
Hypothetical protein.
       0.805
Tmel_0773
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein.
       0.799
Tmel_0777
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
       0.791
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
     0.790
Tmel_0779
PFAM: UvrD/REP helicase.
       0.788
Tmel_0776
Hypothetical protein.
       0.787
Tmel_0778
PFAM: protein of unknown function DUF72.
       0.780
Tmel_0772
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.
       0.773
Tmel_0770
PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain.
       0.762
Tmel_0771
TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase.
       0.762
Your Current Organism:
Thermosipho melanesiensis
NCBI taxonomy Id: 391009
Other names: T. melanesiensis BI429, Thermosipho melanesiensis BI429, Thermosipho melanesiensis str. BI429, Thermosipho melanesiensis strain BI429
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.