node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tmel_1175 | Tmel_1181 | Tmel_1175 | Tmel_1181 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | PFAM: histone deacetylase superfamily. | 0.793 |
Tmel_1175 | Tmel_1182 | Tmel_1175 | Tmel_1182 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | 0.797 |
Tmel_1175 | Tmel_1183 | Tmel_1175 | Tmel_1183 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family. | 0.777 |
Tmel_1175 | Tmel_1185 | Tmel_1175 | Tmel_1185 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | Hypothetical protein. | 0.764 |
Tmel_1175 | gltX2 | Tmel_1175 | Tmel_1176 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.807 |
Tmel_1175 | gyrA | Tmel_1175 | Tmel_1186 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.807 |
Tmel_1175 | lexA | Tmel_1175 | Tmel_1184 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.789 |
Tmel_1175 | metG | Tmel_1175 | Tmel_1187 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.777 |
Tmel_1181 | Tmel_1175 | Tmel_1181 | Tmel_1175 | PFAM: histone deacetylase superfamily. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | 0.793 |
Tmel_1181 | Tmel_1182 | Tmel_1181 | Tmel_1182 | PFAM: histone deacetylase superfamily. | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | 0.805 |
Tmel_1181 | Tmel_1183 | Tmel_1181 | Tmel_1183 | PFAM: histone deacetylase superfamily. | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family. | 0.780 |
Tmel_1181 | Tmel_1185 | Tmel_1181 | Tmel_1185 | PFAM: histone deacetylase superfamily. | Hypothetical protein. | 0.777 |
Tmel_1181 | gltX2 | Tmel_1181 | Tmel_1176 | PFAM: histone deacetylase superfamily. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.809 |
Tmel_1181 | gyrA | Tmel_1181 | Tmel_1186 | PFAM: histone deacetylase superfamily. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.784 |
Tmel_1181 | lexA | Tmel_1181 | Tmel_1184 | PFAM: histone deacetylase superfamily. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.781 |
Tmel_1181 | metG | Tmel_1181 | Tmel_1187 | PFAM: histone deacetylase superfamily. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.835 |
Tmel_1182 | Tmel_1175 | Tmel_1182 | Tmel_1175 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase. | 0.797 |
Tmel_1182 | Tmel_1181 | Tmel_1182 | Tmel_1181 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | PFAM: histone deacetylase superfamily. | 0.805 |
Tmel_1182 | Tmel_1183 | Tmel_1182 | Tmel_1183 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family. | 0.787 |
Tmel_1182 | Tmel_1185 | Tmel_1182 | Tmel_1185 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | Hypothetical protein. | 0.777 |