node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHF_0528 | EHF_0563 | EHF_0528 | EHF_0563 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | 2Fe-2S iron-sulfur cluster binding domain protein. | 0.618 |
EHF_0528 | fabD | EHF_0528 | EHF_0202 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | Malonyl CoA-acyl carrier protein transacylase. | 0.794 |
EHF_0528 | fabF | EHF_0528 | EHF_0770 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.710 |
EHF_0528 | fabG | EHF_0528 | EHF_0596 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.773 |
EHF_0528 | fabH | EHF_0528 | EHF_0392 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | 3-oxoacyl-[acyl-carrier-] synthase III family protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.682 |
EHF_0528 | fabI | EHF_0528 | EHF_0712 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | Enoyl-[acyl-carrier-protein] reductase. | 0.543 |
EHF_0528 | fabZ | EHF_0528 | EHF_0107 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.690 |
EHF_0528 | guaB | EHF_0528 | EHF_0199 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.423 |
EHF_0528 | tme | EHF_0528 | EHF_0885 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | NADP-dependent malic enzyme. | 0.793 |
EHF_0563 | EHF_0528 | EHF_0563 | EHF_0528 | 2Fe-2S iron-sulfur cluster binding domain protein. | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | 0.618 |
EHF_0563 | fabG | EHF_0563 | EHF_0596 | 2Fe-2S iron-sulfur cluster binding domain protein. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.667 |
EHF_0563 | tme | EHF_0563 | EHF_0885 | 2Fe-2S iron-sulfur cluster binding domain protein. | NADP-dependent malic enzyme. | 0.478 |
fabD | EHF_0528 | EHF_0202 | EHF_0528 | Malonyl CoA-acyl carrier protein transacylase. | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain protein. | 0.794 |
fabD | fabF | EHF_0202 | EHF_0770 | Malonyl CoA-acyl carrier protein transacylase. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
fabD | fabG | EHF_0202 | EHF_0596 | Malonyl CoA-acyl carrier protein transacylase. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.973 |
fabD | fabH | EHF_0202 | EHF_0392 | Malonyl CoA-acyl carrier protein transacylase. | 3-oxoacyl-[acyl-carrier-] synthase III family protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.998 |
fabD | fabI | EHF_0202 | EHF_0712 | Malonyl CoA-acyl carrier protein transacylase. | Enoyl-[acyl-carrier-protein] reductase. | 0.987 |
fabD | fabZ | EHF_0202 | EHF_0107 | Malonyl CoA-acyl carrier protein transacylase. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.912 |
fabD | guaB | EHF_0202 | EHF_0199 | Malonyl CoA-acyl carrier protein transacylase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.457 |
fabD | polA | EHF_0202 | EHF_0961 | Malonyl CoA-acyl carrier protein transacylase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.551 |