STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_0358PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_3217 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (318 aa)    
Predicted Functional Partners:
ilvD
KEGG: stp:Strop_1231 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.824
Sare_0356
PFAM: Lantibiotic dehydratase domain protein; KEGG: mxa:MXAN_3624 hypothetical protein.
 
     0.803
Sare_0357
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_4110 putative non-ribosomal peptide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
    0.777
Sare_0355
PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: sma:SAV3641 putative ornithine carbamoyltransferase.
  
    0.728
Sare_1124
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: stp:Strop_1234 acetolactate synthase, small subunit.
  
  
 0.706
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.692
Sare_3392
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: stp:Strop_3167 ferredoxin-dependent glutamate synthase.
  
 
 0.680
Sare_0354
Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.594
Sare_1130
TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: stp:Strop_1240 branched-chain amino acid aminotransferase.
  
  
 0.554
Sare_0353
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D.
  
    0.545
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.