STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_0510Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (375 aa)    
Predicted Functional Partners:
Sare_1126
TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: stp:Strop_1236 D-3-phosphoglycerate dehydrogenase.
 0.984
Sare_0567
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mka:MK0297 predicted dehydrogenase related to phosphoglycerate dehydrogenase.
 
 0.981
Sare_0305
TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_0263 threonine synthase.
   
 0.930
Sare_4032
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.930
Sare_4509
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_4089 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.912
Sare_4585
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_2310 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.908
Sare_0511
PFAM: Citrate synthase; KEGG: stp:Strop_0423 citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.825
Sare_1117
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: stp:Strop_1225 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
 
 0.783
Sare_1953
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rrs:RoseRS_0271 D-3-phosphoglycerate dehydrogenase.
  
 
 0.760
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.754
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.