STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_0630Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (165 aa)    
Predicted Functional Partners:
Sare_2325
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.970
Sare_2059
PFAM: purine or other phosphorylase family 1; KEGG: stp:Strop_4371 purine or other phosphorylase, family 1.
 
 
 0.949
Sare_0863
Cystathionine gamma-synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: stp:Strop_0920 cystathionine gamma-synthase.
 
 
 0.942
Sare_0855
TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_0912 cystathionine beta-synthase.
  
 
 0.928
Sare_2956
TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tfu:Tfu_0438 cystathionine beta-synthase.
  
 
 0.928
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.908
Sare_1736
KEGG: stp:Strop_0966 adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; S-adenosyl-L-homocysteine hydrolase, NAD binding.
    
 0.908
Sare_2784
PFAM: aminotransferase class I and II; KEGG: stp:Strop_2586 aminotransferase, class I and II.
     
  0.900
Sare_1158
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: stp:Strop_1267 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme.
 
 
 0.889
Sare_4509
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_4089 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.839
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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