STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_0776KEGG: stp:Strop_0832 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (527 aa)    
Predicted Functional Partners:
Sare_4204
PFAM: cobalamin B12-binding domain protein; KEGG: stp:Strop_3814 cobalamin B12-binding domain protein.
 0.999
Sare_3990
KEGG: stp:Strop_3609 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase.
  
 0.994
Sare_3993
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: stp:Strop_3611 glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.983
Sare_2155
KEGG: dge:Dgeo_1790 glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.963
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.911
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.910
Sare_3989
KEGG: stp:Strop_3608 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
  
  
 
0.905
Sare_0646
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: stp:Strop_0699 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.867
Sare_2284
KEGG: stp:Strop_2136 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
     
 0.820
Sare_0645
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: stp:Strop_0698 thiamine pyrophosphate enzyme domain protein TPP-binding.
     
 0.814
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.