node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sare_0002 | Sare_0479 | Sare_0002 | Sare_0479 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; DNA polymerase III beta chain; KEGG: sco:SCO1180 DNA polymerase III beta chain. | 0.473 |
Sare_0002 | polA | Sare_0002 | Sare_3372 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.987 |
Sare_0002 | rnhB | Sare_0002 | Sare_1201 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.898 |
Sare_0479 | Sare_0002 | Sare_0479 | Sare_0002 | Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; DNA polymerase III beta chain; KEGG: sco:SCO1180 DNA polymerase III beta chain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.473 |
Sare_0479 | polA | Sare_0479 | Sare_3372 | Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; DNA polymerase III beta chain; KEGG: sco:SCO1180 DNA polymerase III beta chain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.983 |
Sare_0479 | rnhB | Sare_0479 | Sare_1201 | Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; DNA polymerase III beta chain; KEGG: sco:SCO1180 DNA polymerase III beta chain. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.886 |
Sare_1199 | Sare_1200 | Sare_1199 | Sare_1200 | KEGG: stp:Strop_1310 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family. | TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: stp:Strop_1311 signal peptidase I; Belongs to the peptidase S26 family. | 0.977 |
Sare_1199 | Sare_1202 | Sare_1199 | Sare_1202 | KEGG: stp:Strop_1310 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family. | KEGG: stp:Strop_1313 hypothetical protein. | 0.516 |
Sare_1199 | rnhB | Sare_1199 | Sare_1201 | KEGG: stp:Strop_1310 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.869 |
Sare_1200 | Sare_1199 | Sare_1200 | Sare_1199 | TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: stp:Strop_1311 signal peptidase I; Belongs to the peptidase S26 family. | KEGG: stp:Strop_1310 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family. | 0.977 |
Sare_1200 | Sare_1202 | Sare_1200 | Sare_1202 | TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: stp:Strop_1311 signal peptidase I; Belongs to the peptidase S26 family. | KEGG: stp:Strop_1313 hypothetical protein. | 0.666 |
Sare_1200 | rnhB | Sare_1200 | Sare_1201 | TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: stp:Strop_1311 signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.905 |
Sare_1202 | Sare_1199 | Sare_1202 | Sare_1199 | KEGG: stp:Strop_1313 hypothetical protein. | KEGG: stp:Strop_1310 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family. | 0.516 |
Sare_1202 | Sare_1200 | Sare_1202 | Sare_1200 | KEGG: stp:Strop_1313 hypothetical protein. | TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: stp:Strop_1311 signal peptidase I; Belongs to the peptidase S26 family. | 0.666 |
Sare_1202 | rnhB | Sare_1202 | Sare_1201 | KEGG: stp:Strop_1313 hypothetical protein. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.919 |
Sare_1753 | rnhB | Sare_1753 | Sare_1201 | KEGG: stp:Strop_1767 hypothetical protein. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.811 |
Sare_1889 | rnhB | Sare_1889 | Sare_1201 | PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: fra:Francci3_1593 AMP-dependent synthetase and ligase. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.847 |
Sare_3595 | polA | Sare_3595 | Sare_3372 | PFAM: ribonuclease H; Phosphoglycerate mutase; KEGG: stp:Strop_3355 phosphoglycerate mutase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.791 |
Sare_3595 | rnhB | Sare_3595 | Sare_1201 | PFAM: ribonuclease H; Phosphoglycerate mutase; KEGG: stp:Strop_3355 phosphoglycerate mutase. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.903 |
coaE | polA | Sare_3368 | Sare_3372 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.896 |