STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_1925KEGG: stp:Strop_0061 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (98 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.922
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.905
Sare_1736
KEGG: stp:Strop_0966 adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; S-adenosyl-L-homocysteine hydrolase, NAD binding.
     
 0.905
Sare_2059
PFAM: purine or other phosphorylase family 1; KEGG: stp:Strop_4371 purine or other phosphorylase, family 1.
    
  0.902
Sare_1926
PFAM: Bifunctional DNA primase/polymerase; KEGG: stp:Strop_0062 hypothetical protein.
       0.800
Sare_1928
KEGG: sen:SACE_7024 hypothetical protein.
  
  
 0.791
Sare_1927
Hypothetical protein.
       0.773
Sare_1924
KEGG: pna:Pnap_0963 hypothetical protein.
 
    0.597
Sare_1929
PFAM: cell divisionFtsK/SpoIIIE; KEGG: sen:SACE_7023 hypothetical protein.
  
    0.495
Sare_1373
PFAM: membrane-bound metal-dependent hydrolase; KEGG: sma:SAV1574 integral membrane protein.
   
    0.479
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.