STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_3214TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_2992 methylmalonate-semialdehyde dehydrogenase. (496 aa)    
Predicted Functional Partners:
Sare_3215
PFAM: aminotransferase class-III; KEGG: stp:Strop_2993 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.983
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.933
Sare_2204
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: bra:BRADO6191 putative 3-hydroxyisobutyrate dehydrogenase family protein.
 
 
 0.926
Sare_2802
PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_2603 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.925
Sare_2960
PFAM: aminotransferase class-III; KEGG: sco:SCO3622 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.922
Sare_4072
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.922
Sare_0771
PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0827 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
  
  
 
0.921
Sare_0238
PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0078 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.919
Sare_0802
PFAM: carboxyl transferase; KEGG: stp:Strop_0856 carboxyl transferase.
   
 0.908
Sare_3624
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: stp:Strop_3382 propionyl-CoA carboxylase.
   
 0.908
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.