| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Sare_2700 | Sare_2702 | Sare_2700 | Sare_2702 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | 0.999 |
| Sare_2700 | Sare_2705 | Sare_2700 | Sare_2705 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: stp:Strop_2523 precorrin-4 C11-methyltransferase. | 0.995 |
| Sare_2700 | Sare_2706 | Sare_2700 | Sare_2706 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: stp:Strop_2524 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.993 |
| Sare_2700 | Sare_2708 | Sare_2700 | Sare_2708 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: stp:Strop_2526 cob(I)alamin adenosyltransferase. | 0.932 |
| Sare_2700 | Sare_3545 | Sare_2700 | Sare_3545 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | Cobalbumin biosynthesis protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; cobalbumin biosynthesis protein; KEGG: stp:Strop_3313 cobalbumin biosynthesis protein. | 0.938 |
| Sare_2700 | Sare_3922 | Sare_2700 | Sare_3922 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | PFAM: aminotransferase class I and II; KEGG: stp:Strop_3547 aminotransferase, class I and II. | 0.552 |
| Sare_2700 | cobB | Sare_2700 | Sare_2707 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.999 |
| Sare_2700 | cobD | Sare_2700 | Sare_3929 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.917 |
| Sare_2700 | cobQ | Sare_2700 | Sare_3928 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
| Sare_2700 | cobS | Sare_2700 | Sare_3546 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.852 |
| Sare_2702 | Sare_2700 | Sare_2702 | Sare_2700 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: stp:Strop_2518 precorrin-8X methylmutase CbiC/CobH. | 0.999 |
| Sare_2702 | Sare_2705 | Sare_2702 | Sare_2705 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: stp:Strop_2523 precorrin-4 C11-methyltransferase. | 0.999 |
| Sare_2702 | Sare_2706 | Sare_2702 | Sare_2706 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: stp:Strop_2524 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
| Sare_2702 | Sare_2708 | Sare_2702 | Sare_2708 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: stp:Strop_2526 cob(I)alamin adenosyltransferase. | 0.974 |
| Sare_2702 | Sare_3545 | Sare_2702 | Sare_3545 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | Cobalbumin biosynthesis protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; cobalbumin biosynthesis protein; KEGG: stp:Strop_3313 cobalbumin biosynthesis protein. | 0.991 |
| Sare_2702 | Sare_3922 | Sare_2702 | Sare_3922 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | PFAM: aminotransferase class I and II; KEGG: stp:Strop_3547 aminotransferase, class I and II. | 0.703 |
| Sare_2702 | cobB | Sare_2702 | Sare_2707 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.997 |
| Sare_2702 | cobD | Sare_2702 | Sare_3929 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.955 |
| Sare_2702 | cobQ | Sare_2702 | Sare_3928 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.997 |
| Sare_2702 | cobS | Sare_2702 | Sare_3546 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17-methyltransferase. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.989 |