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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_0010PFAM: Aldehyde Dehydrogenase; KEGG: bxe:Bxe_A4441 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
Bphy_1850
PFAM: AMP-dependent synthetase and ligase; KEGG: bxe:Bxe_A1395 putative acetyl-CoA synthetase.
  
 0.924
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.924
Bphy_4939
PFAM: AMP-dependent synthetase and ligase; KEGG: bur:Bcep18194_C6650 AMP-dependent synthetase and ligase.
  
 0.924
Bphy_5127
PFAM: AMP-dependent synthetase and ligase; KEGG: bxe:Bxe_B1085 AMP-binding enzyme.
  
 0.924
Bphy_0483
TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_A0713 glutathione-dependent formaldehyde dehydrogenase(FlhA); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.918
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.916
Bphy_3325
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_B1754 zinc-containing alcohol dehydrogenase superfamily.
  
 
 0.912
Bphy_4997
PFAM: aldo/keto reductase; KEGG: aba:Acid345_2661 aldehyde reductase.
   
 0.912
Bphy_5095
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bxe:Bxe_B2374 putative pyruvate dehydrogenase; Belongs to the TPP enzyme family.
  
 0.910
Bphy_5492
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bxe:Bxe_C1284 putative thiamine pyrophosphate requiring enzyme; Belongs to the TPP enzyme family.
  
 0.910
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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