STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_0305PFAM: glycosyl transferase family 3; KEGG: bxe:Bxe_A4143 putative glycosyl transferase. (322 aa)    
Predicted Functional Partners:
Bphy_2495
TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: bxe:Bxe_A3959 para-aminobenzoate synthase, component I.
 
 
 0.972
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 
 0.902
Bphy_2699
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: bxe:Bxe_A0460 glutamine amidotransferase of anthranilate synthase.
  
  
 0.830
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: bxe:Bxe_A0458 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
  
  
 0.830
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: bxe:Bxe_B2882 phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
  
  
 0.830
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
  
 0.830
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
  
 0.827
Bphy_0741
TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase.
  
  
 0.567
Bphy_0208
PFAM: protein of unknown function DUF330; KEGG: bxe:Bxe_A4222 hypothetical protein.
  
    0.557
Bphy_0192
KEGG: bxe:Bxe_A4239 hypothetical protein.
  
     0.528
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.