node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bphy_0572 | Bphy_0575 | Bphy_0572 | Bphy_0575 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: bxe:Bxe_A0808 riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.811 |
Bphy_0572 | Bphy_0977 | Bphy_0572 | Bphy_0977 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bxe:Bxe_A2333 cystathionine beta-lyase. | 0.831 |
Bphy_0572 | Bphy_4792 | Bphy_0572 | Bphy_4792 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: bxe:Bxe_C0167 putative cytochrome c oxidase subunit II. | 0.667 |
Bphy_0572 | Bphy_5482 | Bphy_0572 | Bphy_5482 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | KEGG: reu:Reut_B3581 cystathionine beta-lyase, bacterial; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.828 |
Bphy_0572 | coaD | Bphy_0572 | Bphy_0310 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.946 |
Bphy_0572 | coaX | Bphy_0572 | Bphy_0203 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.943 |
Bphy_0572 | dut | Bphy_0572 | Bphy_0570 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.938 |
Bphy_0572 | lspA | Bphy_0572 | Bphy_0573 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.668 |
Bphy_0572 | panC | Bphy_0572 | Bphy_2197 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.906 |
Bphy_0572 | priA | Bphy_0572 | Bphy_3022 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.735 |
Bphy_0575 | Bphy_0572 | Bphy_0575 | Bphy_0572 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: bxe:Bxe_A0808 riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.811 |
Bphy_0575 | coaD | Bphy_0575 | Bphy_0310 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: bxe:Bxe_A0808 riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.750 |
Bphy_0575 | lspA | Bphy_0575 | Bphy_0573 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: bxe:Bxe_A0808 riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.780 |
Bphy_0977 | Bphy_0572 | Bphy_0977 | Bphy_0572 | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bxe:Bxe_A2333 cystathionine beta-lyase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.831 |
Bphy_0977 | Bphy_5482 | Bphy_0977 | Bphy_5482 | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bxe:Bxe_A2333 cystathionine beta-lyase. | KEGG: reu:Reut_B3581 cystathionine beta-lyase, bacterial; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.907 |
Bphy_4792 | Bphy_0572 | Bphy_4792 | Bphy_0572 | TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: bxe:Bxe_C0167 putative cytochrome c oxidase subunit II. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.667 |
Bphy_5482 | Bphy_0572 | Bphy_5482 | Bphy_0572 | KEGG: reu:Reut_B3581 cystathionine beta-lyase, bacterial; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.828 |
Bphy_5482 | Bphy_0977 | Bphy_5482 | Bphy_0977 | KEGG: reu:Reut_B3581 cystathionine beta-lyase, bacterial; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bxe:Bxe_A2333 cystathionine beta-lyase. | 0.907 |
coaD | Bphy_0572 | Bphy_0310 | Bphy_0572 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.946 |
coaD | Bphy_0575 | Bphy_0310 | Bphy_0575 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: bxe:Bxe_A0808 riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.750 |