STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_0837Protease Do; KEGG: bxe:Bxe_A1081 subfamily S1C, unassigned peptidase; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. (502 aa)    
Predicted Functional Partners:
Bphy_0835
PFAM: Anti sigma-E protein RseA family protein; KEGG: bxe:Bxe_A1079 anti sigma-E protein, RseA.
  
 
 0.918
Bphy_0471
Protease Do; KEGG: bxe:Bxe_A0701 serine protease, subfamily S1C; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.
  
  
 
0.907
Bphy_0838
PFAM: glutaredoxin 2; KEGG: bxe:Bxe_A1082 hypothetical protein.
  
   0.807
Bphy_0836
PFAM: MucB/RseB family protein; KEGG: bxe:Bxe_A1080 putative sigma E regulatory protein, MucB/RseB.
  
  
 0.777
Bphy_5175
PFAM: CheB methylesterase; MCP methyltransferase CheR-type; KEGG: reu:Reut_B5191 CheB methylesterase:MCP methyltransferase, CheR-type.
  
  
 0.701
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.663
Bphy_0135
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; KEGG: bxe:Bxe_B0221 multi-sensor hybrid histidine kinase.
  
  
 0.650
Bphy_0840
KEGG: bxe:Bxe_A1084 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family.
 
   
 0.625
Bphy_3384
PFAM: NLP/P60 protein; KEGG: rso:RSc1695 probable phage HK022 GP19-related protein.
  
 0.579
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.558
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.