Bphy_2541 protein (Paraburkholderia phymatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Bphy_2541

NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (483 aa)

Predicted Functional Partners:

Bphy_2542

0.999

Bphy_2543

0.999

Bphy_5016

0.922

nadE

0.918

nadE-2

0.908

nadK

0.907

nadD

0.904

Bphy_3717

0.900

Bphy_2540

0.459

nudJ

0.422

Your Current Organism:

Paraburkholderia phymatum

NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bphy_2540	Bphy_2541	Bphy_2540	Bphy_2541	Hypothetical protein.	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.459
Bphy_2540	Bphy_2542	Bphy_2540	Bphy_2542	Hypothetical protein.	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	0.459
Bphy_2541	Bphy_2540	Bphy_2541	Bphy_2540	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Hypothetical protein.	0.459
Bphy_2541	Bphy_2542	Bphy_2541	Bphy_2542	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	0.999
Bphy_2541	Bphy_2543	Bphy_2541	Bphy_2543	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: bxe:Bxe_A4008 putative NAD(P) transhydrogenase, alpha subunit.	0.999
Bphy_2541	Bphy_3717	Bphy_2541	Bphy_3717	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: bxe:Bxe_A2188 putative phosphohydrolase, MutT/NUDIX.	0.900
Bphy_2541	Bphy_5016	Bphy_2541	Bphy_5016	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: reu:Reut_B5878 alanine dehydrogenase and pyridine nucleotide transhydrogenase; Belongs to the AlaDH/PNT family.	0.922
Bphy_2541	nadD	Bphy_2541	Bphy_2067	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.904
Bphy_2541	nadE	Bphy_2541	Bphy_2169	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.918
Bphy_2541	nadE-2	Bphy_2541	Bphy_4778	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.908
Bphy_2541	nadK	Bphy_2541	Bphy_2504	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.907
Bphy_2541	nudJ	Bphy_2541	Bphy_2544	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	PFAM: NUDIX hydrolase; KEGG: bxe:Bxe_A4009 putative NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.	0.422
Bphy_2542	Bphy_2540	Bphy_2542	Bphy_2540	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	Hypothetical protein.	0.459
Bphy_2542	Bphy_2541	Bphy_2542	Bphy_2541	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.999
Bphy_2542	Bphy_2543	Bphy_2542	Bphy_2543	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: bxe:Bxe_A4008 putative NAD(P) transhydrogenase, alpha subunit.	0.999
Bphy_2542	Bphy_3717	Bphy_2542	Bphy_3717	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: bxe:Bxe_A2188 putative phosphohydrolase, MutT/NUDIX.	0.900
Bphy_2542	Bphy_5016	Bphy_2542	Bphy_5016	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: reu:Reut_B5878 alanine dehydrogenase and pyridine nucleotide transhydrogenase; Belongs to the AlaDH/PNT family.	0.408
Bphy_2542	nadD	Bphy_2542	Bphy_2067	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.908
Bphy_2542	nadE	Bphy_2542	Bphy_2169	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.908
Bphy_2542	nadE-2	Bphy_2542	Bphy_4778	KEGG: bcn:Bcen_0217 NAD/NADP transhydrogenase alpha subunit-like.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.902

page 1 of 4

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2023

Credits

Access

Info

About