node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bphy_1317 | Bphy_2707 | Bphy_1317 | Bphy_2707 | PFAM: cyclase/dehydrase; KEGG: bte:BTH_I2050 streptomyces cyclase/dehydrase superfamily. | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 0.602 |
Bphy_1317 | ubiA | Bphy_1317 | Bphy_2519 | PFAM: cyclase/dehydrase; KEGG: bte:BTH_I2050 streptomyces cyclase/dehydrase superfamily. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.469 |
Bphy_1317 | ubiB | Bphy_1317 | Bphy_0377 | PFAM: cyclase/dehydrase; KEGG: bte:BTH_I2050 streptomyces cyclase/dehydrase superfamily. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.457 |
Bphy_1317 | ubiG | Bphy_1317 | Bphy_0736 | PFAM: cyclase/dehydrase; KEGG: bte:BTH_I2050 streptomyces cyclase/dehydrase superfamily. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.651 |
Bphy_2653 | Bphy_2707 | Bphy_2653 | Bphy_2707 | PFAM: Polyprenyl synthetase; KEGG: bxe:Bxe_A0506 octylprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 0.484 |
Bphy_2653 | ubiA | Bphy_2653 | Bphy_2519 | PFAM: Polyprenyl synthetase; KEGG: bxe:Bxe_A0506 octylprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.905 |
Bphy_2653 | ubiG | Bphy_2653 | Bphy_0736 | PFAM: Polyprenyl synthetase; KEGG: bxe:Bxe_A0506 octylprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.419 |
Bphy_2706 | Bphy_2707 | Bphy_2706 | Bphy_2707 | Putative thiol-disulfide interchange protein, DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 0.550 |
Bphy_2707 | Bphy_1317 | Bphy_2707 | Bphy_1317 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | PFAM: cyclase/dehydrase; KEGG: bte:BTH_I2050 streptomyces cyclase/dehydrase superfamily. | 0.602 |
Bphy_2707 | Bphy_2653 | Bphy_2707 | Bphy_2653 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | PFAM: Polyprenyl synthetase; KEGG: bxe:Bxe_A0506 octylprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.484 |
Bphy_2707 | Bphy_2706 | Bphy_2707 | Bphy_2706 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | Putative thiol-disulfide interchange protein, DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.550 |
Bphy_2707 | Bphy_2723 | Bphy_2707 | Bphy_2723 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: bam:Bamb_0412 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.564 |
Bphy_2707 | hemF | Bphy_2707 | Bphy_2066 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.628 |
Bphy_2707 | ubiA | Bphy_2707 | Bphy_2519 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.696 |
Bphy_2707 | ubiB | Bphy_2707 | Bphy_0377 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.555 |
Bphy_2707 | ubiD | Bphy_2707 | Bphy_0614 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.923 |
Bphy_2707 | ubiG | Bphy_2707 | Bphy_0736 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.972 |
Bphy_2707 | ubiX | Bphy_2707 | Bphy_2724 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.911 |
Bphy_2723 | Bphy_2707 | Bphy_2723 | Bphy_2707 | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: bam:Bamb_0412 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0452 putative 2-polyprenyl-3-methyl-6-methoxyphenolhydroxylase, UbiH/VisC-like. | 0.564 |
Bphy_2723 | ubiB | Bphy_2723 | Bphy_0377 | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: bam:Bamb_0412 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.402 |