STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_3178PFAM: CoA-binding domain protein; KEGG: rle:pRL120177 putative pimeloyl-CoA synthetase. (718 aa)    
Predicted Functional Partners:
Bphy_4922
PFAM: Thiolase; KEGG: acr:Acry_2397 propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.925
Bphy_1588
TIGRFAM: propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: bxe:Bxe_A1339 acetyl-coenzyme A synthetase.
 
  
 0.923
Bphy_1850
PFAM: AMP-dependent synthetase and ligase; KEGG: bxe:Bxe_A1395 putative acetyl-CoA synthetase.
 
  
 0.921
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.920
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.918
Bphy_4125
PFAM: acylphosphatase; KEGG: bxe:Bxe_B0023 putative acylphosphatase protein.
  
  
 0.913
Bphy_4355
KEGG: bxe:Bxe_B2900 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.910
Bphy_5095
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bxe:Bxe_B2374 putative pyruvate dehydrogenase; Belongs to the TPP enzyme family.
   
  0.910
Bphy_5492
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bxe:Bxe_C1284 putative thiamine pyrophosphate requiring enzyme; Belongs to the TPP enzyme family.
   
  0.910
Bphy_0178
KEGG: bxe:Bxe_A4255 putative acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.909
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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