STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
betBBetaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (489 aa)    
Predicted Functional Partners:
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
 
 0.983
Bphy_4867
PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: csa:Csal_2458 glucose-methanol-choline oxidoreductase.
 
 
 0.926
Bphy_2379
PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: bam:Bamb_4293 glucose-methanol-choline oxidoreductase.
 
 
 0.921
Bphy_3050
PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: bxe:Bxe_A0016 oxidoreductase, GMC family.
 
 0.921
Bphy_4241
PFAM: Aldehyde Dehydrogenase; KEGG: bxe:Bxe_B0183 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.910
Bphy_3951
PFAM: Rieske [2Fe-2S] domain protein; KEGG: bxe:Bxe_B2830 putative osmotic adaptation-related protein.
   
 
 0.902
betI
Transcriptional regulator, TetR family; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
     0.796
Bphy_3307
TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_B1589 glutathione-independent formaldehyde dehydrogenase.
  
 
 0.480
Bphy_3311
PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bpd:BURPS668_A1931 permeases of the major facilitator superfamily.
  
    0.474
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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