Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_4331PFAM: regulatory protein LuxR; response regulator receiver; KEGG: bxe:Bxe_B2928 two component transcriptional regulator, LuxR family. (212 aa)    
Predicted Functional Partners:
Bphy_1145
Multi-sensor signal transduction histidine kinase; KEGG: bmn:BMA10247_A1432 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.853
Bphy_1512
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: bxe:Bxe_A1456 periplasmic sensor signal transduction histidine kinase.
 
 
 0.849
Bphy_1092
KEGG: bvi:Bcep1808_1534 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.843
Bphy_0098
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: bxe:Bxe_A4346 putative signal transduction histidine kinase.
 
 
 0.840
Bphy_4332
PFAM: Hpt domain protein; KEGG: rme:Rmet_5713 Hpt domain protein.
   
 
 0.817
Bphy_5184
KEGG: bvi:Bcep1808_5667 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.817
Bphy_4333
PFAM: response regulator receiver; Hpt domain protein; KEGG: bte:BTH_I2675 sensor histidine kinase/response regulator.
 
 
 
 0.806
Bphy_0355
PFAM: regulatory protein LuxR; response regulator receiver; KEGG: bxe:Bxe_A4070 two component transcriptional regulator, LuxR family.
  
     0.772
Bphy_0135
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; KEGG: bxe:Bxe_B0221 multi-sensor hybrid histidine kinase.
 
 
 0.722
Bphy_0358
KEGG: bxe:Bxe_A4067 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: extracellular solute-binding protein family 3.
 
 
 
 0.712
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
Server load: low (16%) [HD]