STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_4353KEGG: bxe:Bxe_B2902 2-methylcitrate dehydratase; TIGRFAM: 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein. (483 aa)    
Predicted Functional Partners:
Bphy_4355
KEGG: bxe:Bxe_B2900 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.996
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.966
Bphy_4352
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.880
Bphy_4366
KEGG: bxe:Bxe_B2890 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.852
Bphy_5205
KEGG: bxe:Bxe_B1134 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.832
Bphy_3822
TIGRFAM: phosphoenolpyruvate phosphomutase; KEGG: bxe:Bxe_B2235 PepM.
 
  
 0.811
Bphy_5224
KEGG: rso:RSc1448 hypothetical protein.
 
  
 0.794
Bphy_4354
KEGG: bxe:Bxe_B2901 hypothetical protein.
       0.726
Bphy_0550
Citrate synthase; PFAM: regulatory protein MerR; Citrate synthase; KEGG: bxe:Bxe_A0781 bifunctional --transcriptional regulator, MerR family / citrate synthase.
 
  
 0.717
Bphy_4826
KEGG: aae:aq_150 citrate synthase.
  
  
 0.677
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.