STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111144494Pro-neuregulin-1, membrane-bound isoform isoform X1. (853 aa)    
Predicted Functional Partners:
LOC111160180
Receptor tyrosine-protein kinase erbB-3.
    
 0.996
LOC111138855
Receptor protein-tyrosine kinase.
    
 0.989
LOC111151268
Receptor protein-tyrosine kinase.
    
 0.989
LOC111157042
Receptor protein-tyrosine kinase.
    
 0.973
LOC111141189
Pro-neuregulin-2, membrane-bound isoform isoform X2.
     
0.970
LOC111145254
Pro-neuregulin-3, membrane-bound isoform isoform X1.
     
0.912
LOC111156359
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
 0.609
LOC111160496
Disrupted in schizophrenia 1 protein.
    
 
 0.608
LOC111153672
Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family.
      
 0.603
LOC111139028
LOW QUALITY PROTEIN: myelin protein P0.
      
 0.523
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.