STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111145421SH2 domain-containing protein 4B. (362 aa)    
Predicted Functional Partners:
LOC111141691
RING finger protein 37 isoform X1.
      
 0.620
LOC111144106
E3 ubiquitin-protein ligase PDZRN3 isoform X1.
      
 0.620
LOC111157324
Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.
      
 0.620
LOC111161216
Ran guanine nucleotide release factor isoform X1.
      
 0.620
LOC111159602
F-BAR and double SH3 domains protein 2.
    
 
 0.602
LOC111144086
Protein SHQ1 homolog.
   
  
 0.526
LOC111139288
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.501
LOC111156988
Drebrin-like protein isoform X4.
    
 
 0.462
LOC111146978
FERM, RhoGEF and pleckstrin domain-containing protein 1 isoform X1.
      
 0.441
LOC111153960
Hepatocyte cell adhesion molecule.
      
 0.441
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.