STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111145604Zinc-alpha-2-glycoprotein; Belongs to the MHC class I family. (322 aa)    
Predicted Functional Partners:
LOC111152114
Prolactin-inducible protein.
  
 0.979
LOC111158083
Beta-2-glycoprotein 1.
   
 0.649
LOC111159518
Hemopexin.
   
 
 0.617
LOC111144156
Inter-alpha-trypsin inhibitor heavy chain H4.
   
 
 0.599
LOC111152947
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
  
 0.560
LOC111151609
Histidine-rich glycoprotein.
   
  
 0.554
LOC111154190
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
   
  
 0.537
LOC111151449
fetuin-B isoform X1.
   
  
 0.522
LOC111145607
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.512
LOC111156527
Phospholipase B-like; Putative phospholipase.
      
 0.511
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.