STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111146791G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa)    
Predicted Functional Partners:
LOC111160135
Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily.
   
 0.999
LOC111147618
Cyclin-dependent kinase inhibitor 1.
   
 0.990
LOC111140933
S-phase kinase-associated protein 2.
   
 0.977
LOC111144080
M-phase inducer phosphatase 1 isoform X1.
   
 0.977
LOC111146911
Retinoblastoma-associated protein.
   
 0.976
LOC111141245
S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family.
    
 0.975
LOC111142115
Cyclin-dependent kinase inhibitor 1B.
   
 0.975
LOC111150193
Cyclin-dependent kinase inhibitor 1C.
   
 0.975
LOC111141610
Retinoblastoma-like protein 1 isoform X1.
   
 0.974
LOC111157436
Retinoblastoma-like protein 2 isoform X1.
   
 0.974
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.