STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111148047Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1177 aa)    
Predicted Functional Partners:
LOC111155052
DPH3 homolog isoform X1.
      
 0.737
LOC111147658
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.711
LOC111148639
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.711
LOC111140713
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.639
LOC111158660
LOW QUALITY PROTEIN: WD repeat-containing protein 27.
   
 
 0.625
LOC111141555
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
0.522
LOC111145441
Sphingomyelin synthase-related protein 1.
   
  
 0.511
LOC111147537
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
 0.456
LOC111146534
Protein FAM92A isoform X1.
   
  
 0.449
LOC111153819
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
    
 0.448
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.