STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC1111520333-oxo-5-beta-steroid 4-dehydrogenase isoform X1. (326 aa)    
Predicted Functional Partners:
LOC111162271
3 beta-hydroxysteroid dehydrogenase type 7; Belongs to the 3-beta-HSD family.
   
 
 0.971
LOC111154190
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
   
 
 0.943
LOC111158988
5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family.
   
 
 0.937
LOC111143436
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family.
   
 
 0.936
LOC111153410
3-oxo-5-alpha-steroid 4-dehydrogenase 1.
   
 
 0.926
LOC111152239
Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family.
   
 
 0.922
LOC111145221
Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.
   
 
 0.921
LOC111146729
Cytochrome P450 11B1, mitochondrial-like isoform X1; Belongs to the cytochrome P450 family.
   
 
 0.921
LOC111162366
Corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1.
   
 
 0.920
LOC111152836
Corticosteroid 11-beta-dehydrogenase isozyme 2.
   
 
 0.918
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.