LOC111156420 protein (Enhydra lutris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC111156420

acetoacetyl-CoA synthetase isoform X1. (705 aa)

Predicted Functional Partners:

LOC111153681

0.958

LOC111158670

0.950

LOC111143301

0.948

LOC111154677

0.947

LOC111140873

0.940

LOC111155145

0.940

LOC111154765

0.939

LOC111152335

0.938

LOC111150208

0.937

LOC111154403

0.932

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111140873	LOC111143301	A0A2Y9INA7	A0A2Y9IVU5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.914
LOC111140873	LOC111150208	A0A2Y9INA7	A0A2Y9JRN7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Peroxisomal bifunctional enzyme isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.944
LOC111140873	LOC111152335	A0A2Y9INA7	A0A2Y9KAP1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X1.	0.965
LOC111140873	LOC111153681	A0A2Y9INA7	A0A2Y9K609	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.990
LOC111140873	LOC111154677	A0A2Y9INA7	A0A2Y9KAR9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial.	0.916
LOC111140873	LOC111154765	A0A2Y9INA7	A0A2Y9KM72	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1.	0.970
LOC111140873	LOC111155145	A0A2Y9INA7	A0A2Y9KB19	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.440
LOC111140873	LOC111156420	A0A2Y9INA7	A0A2Y9KIS3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	acetoacetyl-CoA synthetase isoform X1.	0.940
LOC111140873	LOC111158670	A0A2Y9INA7	A0A2Y9KS74	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	acetyl-CoA acetyltransferase, cytosolic isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.	0.991
LOC111143301	LOC111140873	A0A2Y9IVU5	A0A2Y9INA7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.914
LOC111143301	LOC111150208	A0A2Y9IVU5	A0A2Y9JRN7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Peroxisomal bifunctional enzyme isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.960
LOC111143301	LOC111152335	A0A2Y9IVU5	A0A2Y9KAP1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X1.	0.970
LOC111143301	LOC111153681	A0A2Y9IVU5	A0A2Y9K609	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.991
LOC111143301	LOC111154403	A0A2Y9IVU5	A0A2Y9KDV2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxybutyrate dehydrogenase type 2.	0.432
LOC111143301	LOC111154677	A0A2Y9IVU5	A0A2Y9KAR9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial.	0.916
LOC111143301	LOC111154765	A0A2Y9IVU5	A0A2Y9KM72	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1.	0.981
LOC111143301	LOC111155145	A0A2Y9IVU5	A0A2Y9KB19	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.623
LOC111143301	LOC111156420	A0A2Y9IVU5	A0A2Y9KIS3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	acetoacetyl-CoA synthetase isoform X1.	0.948
LOC111143301	LOC111158670	A0A2Y9IVU5	A0A2Y9KS74	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	acetyl-CoA acetyltransferase, cytosolic isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.	0.987
LOC111150208	LOC111140873	A0A2Y9JRN7	A0A2Y9INA7	Peroxisomal bifunctional enzyme isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.944