node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC111143936 | LOC111156730 | A0A2Y9IYK6 | A0A2Y9KQA1 | Nucleoredoxin-like protein 1. | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] | 0.584 |
LOC111143936 | LOC111160342 | A0A2Y9IYK6 | A0A2Y9L644 | Nucleoredoxin-like protein 1. | Fascin. | 0.676 |
LOC111149587 | LOC111149694 | A0A2Y9JXW8 | A0A2Y9JYK3 | Fatty acid desaturase 1. | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.910 |
LOC111149587 | LOC111152367 | A0A2Y9JXW8 | A0A2Y9K0D4 | Fatty acid desaturase 1. | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | 0.966 |
LOC111149587 | LOC111153279 | A0A2Y9JXW8 | A0A2Y9KEQ0 | Fatty acid desaturase 1. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.904 |
LOC111149587 | LOC111155584 | A0A2Y9JXW8 | A0A2Y9KQN1 | Fatty acid desaturase 1. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.905 |
LOC111149587 | LOC111156576 | A0A2Y9JXW8 | A0A2Y9KVV5 | Fatty acid desaturase 1. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.904 |
LOC111149587 | LOC111156730 | A0A2Y9JXW8 | A0A2Y9KQA1 | Fatty acid desaturase 1. | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] | 0.960 |
LOC111149587 | LOC111162454 | A0A2Y9JXW8 | A0A2Y9LBJ1 | Fatty acid desaturase 1. | Very-long-chain enoyl-CoA reductase. | 0.912 |
LOC111149694 | LOC111149587 | A0A2Y9JYK3 | A0A2Y9JXW8 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Fatty acid desaturase 1. | 0.910 |
LOC111149694 | LOC111152367 | A0A2Y9JYK3 | A0A2Y9K0D4 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | 0.950 |
LOC111149694 | LOC111153279 | A0A2Y9JYK3 | A0A2Y9KEQ0 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.970 |
LOC111149694 | LOC111155573 | A0A2Y9JYK3 | A0A2Y9KJ92 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | 0.943 |
LOC111149694 | LOC111155584 | A0A2Y9JYK3 | A0A2Y9KQN1 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.970 |
LOC111149694 | LOC111156576 | A0A2Y9JYK3 | A0A2Y9KVV5 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.960 |
LOC111149694 | LOC111156730 | A0A2Y9JYK3 | A0A2Y9KQA1 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] | 0.927 |
LOC111149694 | LOC111162454 | A0A2Y9JYK3 | A0A2Y9LBJ1 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Very-long-chain enoyl-CoA reductase. | 0.975 |
LOC111152367 | LOC111149587 | A0A2Y9K0D4 | A0A2Y9JXW8 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | Fatty acid desaturase 1. | 0.966 |
LOC111152367 | LOC111149694 | A0A2Y9K0D4 | A0A2Y9JYK3 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.950 |
LOC111152367 | LOC111153279 | A0A2Y9K0D4 | A0A2Y9KEQ0 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.913 |