STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111160408BTB/POZ domain-containing protein KCTD2. (263 aa)    
Predicted Functional Partners:
LOC111155833
LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2-like.
   
 0.948
LOC111160800
SUMO-activating enzyme subunit 1 isoform X1.
  
 0.909
LOC111161422
SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.
   
 0.908
LOC111149647
Small ubiquitin-related modifier.
   
 0.907
LOC111157498
Ran GTPase-activating protein 1 isoform X1.
   
 0.904
LOC111141843
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.880
LOC111146535
E3 SUMO-protein ligase NSE2 isoform X1.
   
 0.833
LOC111141412
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.829
LOC111156390
Ubiquitin-conjugating enzyme E2 variant 1-like isoform X1.
   
 0.829
LOC111145904
Zinc finger and BTB domain-containing protein 6.
    
 0.792
Your Current Organism:
Enhydra lutris
NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.