STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABP90168.1Isocitrate dehydrogenase. (393 aa)    
Predicted Functional Partners:
ABP90171.1
Aconitase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.996
ABP90170.1
Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.977
ABP89220.1
NAD(P)H-dependent glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.927
ldh
Malate/lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.886
argH
Argininosuccinate lyase.
     
 0.838
ABP89316.1
Aspartate/tyrosine/aromatic aminotransferase.
   
 
 0.830
ABP89011.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.829
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
0.728
ABP90804.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
   
 
 0.650
ABP90166.1
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
  
 0.578
Your Current Organism:
Streptococcus suis 05ZYH33
NCBI taxonomy Id: 391295
Other names: S. suis 05ZYH33, Streptococcus suis str. 05ZYH33, Streptococcus suis strain 05ZYH33
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.