node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDP94601.1 | EDP95587.1 | KAOT1_04270 | KAOT1_22086 | COG3321 Polyketide synthase modules and related proteins. | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | 0.436 |
EDP94601.1 | EDP97713.1 | KAOT1_04270 | KAOT1_21162 | COG3321 Polyketide synthase modules and related proteins. | Glycine dehydrogenase (decarboxylating), glycine cleavage system P-protein; Belongs to the GcvP family. | 0.466 |
EDP94601.1 | glyA-2 | KAOT1_04270 | KAOT1_04982 | COG3321 Polyketide synthase modules and related proteins. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.785 |
EDP94601.1 | kmo | KAOT1_04270 | KAOT1_22001 | COG3321 Polyketide synthase modules and related proteins. | Monooxygenase, FAD-binding protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.908 |
EDP94797.1 | EDP95587.1 | KAOT1_01185 | KAOT1_22086 | COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | 0.676 |
EDP95586.1 | EDP95587.1 | KAOT1_22081 | KAOT1_22086 | Hypothetical protein; COG3104 Dipeptide/tripeptide permease. | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | 0.536 |
EDP95587.1 | EDP94601.1 | KAOT1_22086 | KAOT1_04270 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | COG3321 Polyketide synthase modules and related proteins. | 0.436 |
EDP95587.1 | EDP94797.1 | KAOT1_22086 | KAOT1_01185 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.676 |
EDP95587.1 | EDP95586.1 | KAOT1_22086 | KAOT1_22081 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | Hypothetical protein; COG3104 Dipeptide/tripeptide permease. | 0.536 |
EDP95587.1 | EDP97713.1 | KAOT1_22086 | KAOT1_21162 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | Glycine dehydrogenase (decarboxylating), glycine cleavage system P-protein; Belongs to the GcvP family. | 0.590 |
EDP95587.1 | EDP98271.1 | KAOT1_22086 | KAOT1_13677 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | Hypothetical protein; COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease. | 0.559 |
EDP95587.1 | EDP98272.1 | KAOT1_22086 | KAOT1_13682 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | Putative phage polynucleotide kinase. | 0.559 |
EDP95587.1 | glyA-2 | KAOT1_22086 | KAOT1_04982 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.409 |
EDP95587.1 | kmo | KAOT1_22086 | KAOT1_22001 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | Monooxygenase, FAD-binding protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.418 |
EDP97713.1 | EDP94601.1 | KAOT1_21162 | KAOT1_04270 | Glycine dehydrogenase (decarboxylating), glycine cleavage system P-protein; Belongs to the GcvP family. | COG3321 Polyketide synthase modules and related proteins. | 0.466 |
EDP97713.1 | EDP95587.1 | KAOT1_21162 | KAOT1_22086 | Glycine dehydrogenase (decarboxylating), glycine cleavage system P-protein; Belongs to the GcvP family. | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | 0.590 |
EDP97713.1 | glyA-2 | KAOT1_21162 | KAOT1_04982 | Glycine dehydrogenase (decarboxylating), glycine cleavage system P-protein; Belongs to the GcvP family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
EDP98271.1 | EDP95587.1 | KAOT1_13677 | KAOT1_22086 | Hypothetical protein; COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease. | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | 0.559 |
EDP98271.1 | EDP98272.1 | KAOT1_13677 | KAOT1_13682 | Hypothetical protein; COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease. | Putative phage polynucleotide kinase. | 0.844 |
EDP98272.1 | EDP95587.1 | KAOT1_13682 | KAOT1_22086 | Putative phage polynucleotide kinase. | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. | 0.559 |