STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB84932.1[I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (709 aa)    
Predicted Functional Partners:
EEB83201.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
 
0.999
EEB83401.1
LAO/AO transport system ATPase; [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.
  
 0.996
mce
methylmalonyl-CoA epimerase; [E] COG0346 Lactoylglutathione lyase and related lyases.
 
  
 0.984
uca
Urea carboxylase; [I] COG0511 Biotin carboxyl carrier protein.
  
 
 0.938
sucD
succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.912
hpaD
3,4-dihydroxyphenylacetate 2,3-dioxygenase; [E] COG0346 Lactoylglutathione lyase and related lyases.
    
 0.912
sucC
succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.908
EEB83560.1
[I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
    
 0.908
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.906
EEB83667.1
2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.901
Your Current Organism:
Roseobacter sp. GAI101
NCBI taxonomy Id: 391589
Other names: R. sp. GAI101
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.