STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dehIIHaloacid dehalogenase, type II; [R] COG1011 Predicted hydrolase (HAD superfamily). (272 aa)    
Predicted Functional Partners:
EEB83096.1
[R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
  0.860
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.832
pcaD
3-oxoadipate enol-lactonase; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
 
  0.825
pcaB
3-carboxy-cis,cis-muconate cycloisomerase; [E] COG0165 Argininosuccinate lyase.
    
  0.814
EEB85817.1
Threonine dehydratase; [E] COG0031 Cysteine synthase.
       0.801
tetA
Tetracycline resistance protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.
       0.775
EEB86339.1
Esterase EstC, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
  0.756
EEB83959.1
Hydrolase, alpha/beta fold family; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
   
 
 0.747
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.742
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.719
Your Current Organism:
Roseobacter sp. GAI101
NCBI taxonomy Id: 391589
Other names: R. sp. GAI101
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.